Biological Fluid Dynamics

Instabilities and mixing in flowing gyrotactic microorganism suspensions


 Pattern prediction of bioconvection under uniform shear

Microorganisms are present in almost every part of temperate aqueous environments, and they play a critical role in pathogenic infection, digestion, reproduction, and food chains in the oceans. Many swimming microorganisms often exhibit collective behaviours, and it often originates from interaction of the microorganisms' motility with surrounding fluid flows. The focus of the current research is aimed at understanding how these collective dynamics of the swimming microorganisms (particularly biflagallate algae, e.g. Chlamydomonas) interact with instabilities in shear flows. Another important recent research is to find efficient mixing strategies of the microorganism suspensions using optimal control theory for biofuel harvesting.

See also.

Stability of downflowing gyrotatic microorganism suspensions in  a two-dimensional vertical channel
Y. Hwang & T. J. Pedley, 2014, 
J. Fluid Mech 749, p750.  

Bioconvection under unform shear: linear stability analysis
Y. Hwang & T. J. Pedley, 2014, J. Fluid Mech. 
738, p522.


Cellular mechanotransduction in vascular flow systems


Signaling cascade over cytoplasm in a cell  predicted by a reaction-diffusion system

The cardiovascular system is particularly interesting in the context of fluid mechanics because hemodynamics (fluid mechanics of blood flow) plays a crucial role in early development of atherosclerosis, the leading cause of heart attacks and strokes. Early atherosclerotic lesions localise preferentially in arterial regions that are exposed to low flow rate and/or oscillatory flow. Development of these lesions involves dysfunction of the vascular endothelium, the monolayer of cells lining the inner surfaces of all blood vessels. Therefore, understanding the processes by which mechanical stimuli are translated into intracellular biochemical responses  (mechanotransduction) is a central research issue. My research was devoted to understanding how mechanical force is transmitted through subcellular structures.

See also:

Model of cellular mechanotransduction via actin stress fibre networks
C. L. M. Gouget, Y. Hwang & A. I. Barakat, 2016, 
Biomech. Model. Mechanobiol. 15(2), p331.

Characterizing cell adhesion using micropipette aspiration
B. Hogan, A. Babataheri, Y. Hwang, A. I. Barakat & J. Husson, 2015Biophys. J. 109, p209.

Intracellular regulation of cell signaling cascades: how location makes difference
Y. Hwang, P. Kumar & A. I. Barakat,
2014,  J. Math. Biol., 69(1), p213.

Mechanisms of cytoskeleton-mediated mechanical signal transmission in cells
Y. Hwang & A. I. Barakat, 2012, Comm. Int. Biol., 5(6) p1.

Dynamics of mechanical signal transmission through prestressed stress fibers
Y. Hwang & A. I. Barakat, 2012, PLoS ONE, 7(4) e35343.


Physical Fluid Dynamics

Physics and control in wall turbulence


Very-large-scale motions in a turbulent channel with (left) and without (right) the near-wall and log-layer eddies

Coherent structures in wall-bounded turbulent flows play an important role in momentum, mass, and heat transfer. Current research is devoted to correctly identify their dynamics using modern hydrodynamic stability theories and dynamical system approaches. Special effort is being made to establish an integrated theoretical descrption that consistently covers from bypass transition to high-Reynolds-number turbulence, combining these approaches with classical theory (Townsend's attached eddy hypothesis).  Another important current research goal is to reduce turbulent skin friction drag by manipulating outer turbulence, and this will have a significant impact in developing in innovative energy utilization processes, vehicle design, and so on.

See also:

On the self-sustained nature of large-scale motions in tubulent Couette flow
S. Rawat, C. Cossu, Y. Hwang & F. Rincon, 2015,
J. Fluid Mech.  782, p515.

Statistical structure of self-sustaining attached eddies in turbulent channel flow
Y. Hwang, 2015, 
J. Fluid Mech., 767, p254.

Near-wall turbulent fluctuations in the absence of wide outer motions
Y. Hwang, 2013,  J. Fluid Mech., 723, p264.

Self-sustained processes in the logarithmic layer of turbulent channel flows
Y. Hwang & C. Cossu, 2011, Phys. Fluids, 23, 061702.

On the stability of large-scale streaks in turbulent Poiseulle and Couette flows
J. Park, Y. Hwang & C. Cossu, 2011, C. R. Mecanique, 339(1), p1.

Optimally amplified large-scale streak and drag reduction in the turbulent pipe flow
A. P. Willis, Y. Hwang & C. Cossu, 2010, Phys. Rev. E 83, 036321.

Self-sustained process at large scale in turbulent channel flow
Y. Hwang & C. Cossu, 2010, Phys. Rev. Lett. 105, 044505. 

Linear non-normal energy amplification of harmonic and stochastic forcing in the turbulent channel flow
Y. Hwang & C. Cossu, 2010, J. Fluid Mech. 664, p51.

Amplification of coherent streaks in the turbulent Couette flow: an input-output analysis at low Reynolds numbers
Y. Hwang & C. Cossu, 2010, J. Fluid Mech. 643, p333.


Physics and control of instabilities in bluff-body wakes


Vortex shedding controlled by spanwise wavy blowing/suction (left) and the related vortex dynamics (right)

The wake behind a bluff body is an important canonical flow for engineering applications, as vortex shedding in wakes is a main source of drag, structural vibration and aeroacoustic noise.  Controlling vortex shedding using spanwise varying passive or active actuation has recently been reported as a very efficient method for regulating bluff-body wakes. My recent research on this issue has been focused on eluminating the mechanism by which this type of controls stabilizes vortex shedding using hydrodynamic stability theory. To this end, I apply Floquet theory to spatiao-temporal dynamics of the near-wake instabilities.

See also:

Structural sensitivities of soft and steep nonlinear global modes in spatially developing media
Y. Hwang, 2014,
Eur. J. Mech. - B/Fluids, 49Part B, p322.

Stabilization of absolute instability in spanwise wavy two-dimensional wake
Y. Hwang, J. Kim & H. Choi, 2013,  J. Fluid Mech.
723, p346.

Sensitivity of global instability of spatially developing flow in weakly and fully nonlinear regimes
Y. Hwang & H. Choi, 2008, Phys. Fluids 20, 071703 

Control of absolute instability by basic-flow modification in a parallel wake at low Reynolds number
Y. Hwang & H. Choi, 2006, J. Fluid Mech. 560 , p465.